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OSM-SMI-10B is a small-molecule research inhibitor that significantly reduces oncostatin M (OSM)-induced STAT3 phosphorylation in cancer cells. It is intended for biochemical and cellular research into JAK/STAT signaling and STAT3-related pathways. The compound is supplied as a high-purity solid and has defined storage conditions for powder and solutions.
Significantly reduces OSM-induced STAT3 phosphorylation in cellular assays.
Directly targets phosphorylated STAT3 (p-STAT3) in the JAK/STAT pathway.
High purity (99.7%) suitable for research applications.
Molecular formula C21H14O7; molecular weight 378.33 g·mol⁻¹.
Powder storage: -20°C for 3 years, 4°C for 2 years.
In solvent storage: -80°C for 6 months, -20°C for 1 month.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
OSM-S-106 is a pro-inhibitor that works by inhibiting PfAsnRS through an enzyme-mediated adduct formation. It effectively blocks protein translation and triggers an amino acid starvation response. The compound demonstrates selective activity against both Plasmodium blood and liver stages, and exhibits low intrinsic clearance by human microsomes.
Inhibits PfAsnRS via an enzyme-mediated adduct.
Blocks protein translation.
Activates amino acid starvation response.
Selectively active against Plasmodium blood and liver stages.
Low intrinsic clearance by human microsomes.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
OSM-S-106 is a pro-inhibitor that inhibits PfAsnRS via enzyme-mediated production of an Asn-OSM-S-106 adduct. It inhibits protein translation and activates the amino acid starvation response. This product exhibits selective activity against Plasmodium blood and liver stages and has low intrinsic clearance by human microsomes.
Inhibits protein translation
Activates the amino acid starvation response
Selective activity against Plasmodium blood and liver stages
Low intrinsic clearance by human microsomes
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Waters TA Instruments Zinc Calibration Material Not Certified is standard zinc material used for temperature calibration of DSC cells, TMA instruments, and other environmental systems, providing a non-certified reference.
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This Standard Reference Material (SRM) provides the high-resolution X-ray diffraction (HRXRD) community with International System of Units (SI) [1] traceable Si (220) d-spacing in transmission surface-to-crystal-plane wafer miscut and surface-to-Si (004) Bragg angle in reflection for our reference wavelength. A unit of SRM 2000 consists of25 mm x 25 mm x 0.725 mm double-polished (100)-oriented single-crystal Si specimens with a nominal 50 nm Si0.85Ge0.15 epitaxial layer and 25 nm Si cap. These certified values can be used to calibrate HRXRD instrumentation. For more information please refer to the SDS and COA.SRM 2000cert SRM 2000 SDS
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